A unique study published in Scientific Reports, an online, open access journal from the publishers of Nature, has used molecular profiles to reveal major differences in composition between a GMO corn and its non-GMO parent.
An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process
Full paper: http://www.nature.com/articles/srep37855
Authors: Robin Mesnage, Sarah Z. Agapito-Tenfen, Vinicius Vilperte, George Renney, Malcolm Ward, Gilles-Eric Séralini, Rubens O. Nodari & Michael N. Antonio
Abstract
Glyphosate tolerant genetically modified (GM) maize NK603 was assessed as ‘substantially equivalent’ to its isogenic counterpart by a nutrient composition analysis in order to be granted market approval. We have applied contemporary in depth molecular profiling methods of NK603 maize kernels (sprayed or unsprayed with Roundup) and the isogenic corn to reassess its substantial equivalence status. Proteome profiles of the maize kernels revealed alterations in the levels of enzymes of glycolysis and TCA cycle pathways, which were reflective of an imbalance in energy metabolism. Changes in proteins and metabolites of glutathione metabolism were indicative of increased oxidative stress. The most pronounced metabolome differences between NK603 and its isogenic counterpart consisted of an increase in polyamines including N-acetyl-cadaverine (2.9-fold), N-acetylputrescine (1.8-fold), putrescine (2.7-fold) and cadaverine (28-fold), which depending on context can be either protective or a cause of toxicity. Our molecular profiling results show that NK603 and its isogenic control are not substantially equivalent.
Endless facts don’t stop our poisoning. The aristocrats are eugenicists: the aristocrats want the common man dead by diseases the aristocrats induce. It is slimy for a common person not to talk about fascist eugenics when it comes to chemicals since all of the 120, 000 chemicals the beasts on top use in industrial production murders people. I am an organic farmer. Spit it out because we are dying and you don’t want to step on the robes of the king. It is conscious hideous psychotic reasoning that motivates the aristocrats to kill their extant slave populations. I am no one to you and I know these things to be true. You do help in the groundswell of resistance, but you must drop your ideological politeness if we are stop the bodies from going to the morgue.